FDA gives Approval to CBD based Epidiolex Drug

The drug that was given approval this week, is a liquid medicine treatment derived from CBD-dominant strains that have been cultivated by GW Pharmaceuticals.  There have been sufficient clinical trials to prove that it significantly reduces the number of seizures suffered by epileptic patients.  Nothing related to the cannabis plant has ever come close to approval from an entity as important as the FDA.  The closest thing to marijuana that has been approved by the FDA is a synthetic version of THC called dronabinol.  It is a man-made version of tetrahydrocannabinol and is not derived from any natural plants.  Its prescribed to cancer patients suffering from nausea as a result of chemotherapy.  This ruling is a much larger step in the right direction because in order for it to be marketed to patients with Dravet or Lennox-Gastaut syndrome, it must be rescheduled by the DEA.  CBD still currently holds a schedule 1 status preventing it from being prescribed to patients.  The Drug Enforcement Agency is expected to do so within 90 days due to the scientific confirmation of its effectiveness through numerous trials.

I believe this is going to start a wave of cannabis-based medicines being introduced into the pharmaceutical environment.  People are going to see the acceptance of Epidiolex as an open door to try and treat other ailments using derivatives from the plant.  The Healthcare and pharmaceutical companies can not make money off something that can be grown from a seed so none of these medicines will be cannabis in its natural form.  In the case of epileptic patients, especially children, smoking the buds from plants is not a viable option.  Children suffering from these awful diseases will no longer have to fear criminal punishment on top of trying to just live a somewhat functional life.  Patients suffering from Dravet Syndrome have an average life expectancy of 8 years (National Institute of Health).

The other disease that this drug can soon be prescribed for is Lennox-Gastaut syndrome.  According to the LGS Foundation, one clinical trial at New York University showed a 47% of patients showed a 50% reduction in seizures after 3 months of treatment.  It’s also important to mention that 9% of these people were actually seizure free at that time frame.  This is just incredible that it is actually eliminating seizures altogether for certain patients.  Results like these are backed up by many other studies that show even higher numbers of participants seeing a large reduction in the number of their seizures. The DEA should see rescheduling CBD as a number one priority for these children.  With limited years to live and any seizure having the potential to be their last, officials need to act fast to provide a reliable source of the medication.  It will be treated like any other prescribed drug and can be picked up from local pharmacies, not compassion centers or dispensaries.

Traditional medical marijuana dispensaries offer a variety of extracts that could work well with seizures as well.  The only difference is they have not been given the attention from government officials that Epidiolex received likely due to its non-psychoactive properties and its easy to use liquid consistency.  Patients will be able to ingest the medicine by the use of a dropper for precise dosing.  This can be done anywhere without drawing any attention that smoking marijuana brings.  It’s also possible that there will be additional medical uses approved by the FDA for this exact same drug with no chemical changes being made.  Its unique features give it a higher potential of being approved than other new and existing marijuana medicines that may be tested by the FDA.

Advertisements

Canadian Senate Legalizes Marijuana

Smoking, possessing, and growing cannabis will no longer be a criminal offense across the nation of Canada thanks to the approval of a legalization bill by the Senate this past Tuesday.  The bill passed with a vote of 52-29.  As of today, the bill has been given royal assent, the final step in the Canadian legislative process.  While it is officially passed, the law does not take effect until October 17th so don’t become careless and be aware you can still be charged with a crime.  The regulation of cannabis will be done in a much different way then it has been done in individual U.S. states.  One of these differences is the minimum age required to legally consume and purchase the plant.  The federal government has set the age at 18, but provinces can set some of their own unique rules and many are expected to add another year to that federal requirement.  Canadian officials argue that setting the age too high will encourage many young adults who will use cannabis regardless to seek out their weed from the black market.  Youth consumption rates in Canda are among the highest in the world, and they believe that setting a similar age to the states will only encourage criminal organizations.

When it comes to possession limits the maximum amount a person can possess is 30 grams.  While an oz is a decent amount for personal use, setting magical limits is kind of a ridiculous practice.  You aren’t allowed to only have 30 cans of beer per person.  Every state so far has also set their own unique limits in the U.S.  The cool thing about the legislation in Canada is there is no possession limit within a private dwelling.  This is a key addition to the law because growing the 4 allowed plants will provide much more than 30 grams of usable cannabis and that’s not taking into consideration leftovers from the last harvest.

Another aspect of the law that makes it unique is the idea of mail order weed.  This is already a practice in the medical marijuana industry for registered patients.  Soon it will become available for recreational users as well.  To protect against youth accessing marijuana, it will not be delivered unless someone is home and able to show I.D. for the package.  There aren’t any specific details regarding how much can be ordered at a time but it can be assumed that it’s the possession limit of 30 grams.  It will be interesting to see how popular this method of purchase will become in comparison to the retail shops that will also be dispensing marijuana.  The convenience of a quick delivery could cause the same problems Amazon has caused for retail shopping giants.

Altogether the Parliment did a good job drafting a well thought out piece of legislation.  They thought about many different factors when drafting the rules with the main one being protecting the youth.  Limiting advertising and lowering the legal age of consumption are just two of the steps they have taken to eliminate the damage from years of prohibition.  The only thing that wasn’t mentioned in the bill that I would have liked to see included would be the expungement of records for those previously convicted of cannabis possession or cultivation crimes.  This will likely be something that happens in the future after the law takes effect but it is a crucial step nonetheless.